a1 agonists
phenylephrine
a2 receptor agonists
clonidine guanfacine
B2 receptor location:
smooth muscle
B1 and B2 mixed agonists
isoprotereonolepinephrine
a1 and a2 receptor antagonists
phentolamine
B3 receptor location
adipocytes
a1 and a2 receptor mixed agonists
NE/E
a1 receptor antagonists
prazosinlebetalol
a2 receptor location
CNS autonomic ganglia
B1 receptor location
heart
B2 receptor antagonists
butoxamine
Nm nicotinic cholinergic antagonists (parasympatholytics)
Tubocurarineα-bungarotoxin
B1 and B2 antagonists
propranololtimolollabetalolcarvedilol
a1 receptor mechanism
couples w/ Gq (Inc. IP3 and DAG)
Nn nicotinic cholinergic antagonists (parasympatholytics)
HexamethoniumTrimethaphan
muscarinic receptor antagonists
AtropineScopolamineIpratropium
B2 receptor agonists
albuterol metaproterenol
a2 receptor antagonists
yohimbine
Nn nicotinic cholinergic agonists (mimetics)
DMPP
muscarinic receptor agonists
AcetylcholineMuscarineCarbacholPilocarpine
B1 receptor agonists
NEDobutamine
B1 receptor antagonists
metoprololatenololbetaxolol
nicotinic cholinergic mixed agonists
AcetylcholineNicotineCarbachol
a2 receptor mechanism
couples via Gi/Go(dec. cAMP)
a1 Receptor location
blood vessels
Nm nicotinic cholinergic agonists (mimetics)
suxamethonium
ALL B receptor mechanisms
couples via Gs (inc. cAMP)